Manufacturer Suppliers
If you supply Cencora's distribution centers, your EDI must support high-volume 850 POs, timely 855 acknowledgments, and invoices that tie exactly to received quantities and contract pricing.
Full EDI compliance for suppliers trading with Cencora (formerly AmerisourceBergen) — order-to-cash, chargebacks, and DSCSA-aligned traceability. 850, 855, 856, 810, 997, 844, 849, 852 and 867 via AS2, SFTP, or VAN. SAP, Oracle, NetSuite, Dynamics 365, and QuickBooks integration included. Fully managed by SBSA Technology.
Cencora suppliers typically operate across three interconnected workflows. SBSA Technology automates all three from a single EDI and ERP integration.
Receive Cencora's purchase order with item, quantity, price, and ship window for distribution center delivery.
Confirm the PO at line-item level with accepted quantity, price, and ship date within Cencora's required window.
Cartons and pallets must carry compliant labeling with lot numbers that match your ASN and product data.
Transmit the ASN before or at the moment your shipment departs, including lot and expiration data.
Submit your EDI invoice post-delivery, matching the PO and ASN exactly to avoid payment delays.
Cencora submits WAC and contract price, quantity, customer, and contract number for each chargeback claim.
Each claim is checked against your contract management data before a response is generated.
Confirm acceptance or dispute discrepancies via EDI 849 within the window your agreement specifies.
Many chargeback and rebate programs require periodic 852 reporting of sell-through activity.
SBSA maps approved chargebacks and rebate credits back into your ERP's financial ledger automatically.
Unit- and case-level serial numbers must accompany shipments to support DSCSA traceability requirements.
Lot numbers and expiration dates carried in the 856 ASN must match physical labeling exactly.
Product Transfer and Resale Reports give Cencora and upstream manufacturers visibility into downstream movement.
Transaction history and statement data must be retrievable to satisfy verification requests.
SBSA flags data mismatches immediately so suspect or recalled product can be traced and isolated quickly.
Cencora (formerly AmerisourceBergen) connects manufacturers, providers, pharmacies, and patients across the healthcare supply chain. Its EDI requirements are strict, high-volume, and tied directly to regulatory obligations — late ASNs, mismatched invoices, or incomplete chargeback responses create compliance and revenue risk.
If you supply Cencora's distribution centers, your EDI must support high-volume 850 POs, timely 855 acknowledgments, and invoices that tie exactly to received quantities and contract pricing.
Manufacturers with contract pricing agreements must validate and respond to 844 chargeback claims accurately and on time, or risk incorrect credits and reconciliation delays.
Suppliers must provide serialized, lot-level product data alongside standard EDI transactions to satisfy the Drug Supply Chain Security Act and Cencora's own tracing requirements.
Cencora supports multiple EDI transmission protocols. SBSA Technology handles setup, configuration, certificate management, and ongoing compliance monitoring for all connection types.
Applicability Statement 2
Direct, encrypted HTTPS connection between your system and Cencora's EDI network. AS2 provides real-time acknowledgment and non-repudiation, making it the preferred protocol for high-volume suppliers.
Secure File Transfer Protocol
File-based EDI transmission via a secure FTP server. SBSA polls the SFTP directory on a defined schedule, picks up inbound documents, and delivers outbound files reliably and without manual intervention.
Value-Added Network
Indirect routing through a third-party EDI network. SBSA connects to your VAN mailbox on your behalf and manages translation and document routing to and from Cencora.
SBSA Technology supports core and supplemental Cencora Integration EDI documents. Critical transactions are highlighted because they carry the highest compliance risk when transmitted incorrectly or late.
Cencora's order to you. Contains item, quantity, price, ship window, and destination distribution center.
InboundYour acceptance or modification of the PO, line by line, including ship date and accepted quantity.
OutboundTransmitted at the moment your shipment leaves. Carries lot, carton, and carrier data. Late = compliance risk.
OutboundSubmitted after delivery confirmation. Must match the PO and ASN exactly to avoid payment delays.
OutboundConfirms receipt of every EDI interchange between you and Cencora.
OutboundPeriodic sell-through and inventory activity data used for rebate and demand visibility programs.
InboundReports downstream product movement, supporting DSCSA traceability and demand analytics.
InboundCencora's chargeback claim, including WAC and contract price, quantity, and customer detail.
InboundYour acceptance or dispute of a chargeback claim, transmitted within the contracted response window.
OutboundSBSA Technology provides pre-built ERP integrations that simplify EDI implementation, automate document exchange, and reduce onboarding time.
Full SAP integration via IDocs or direct API. Maps Cencora's EDI segments to SAP order management, inventory, and FI invoice processing, including chargeback postings.
Bidirectional integration: 850 POs create sales orders in NetSuite automatically; ship confirmations and invoices flow back to Cencora as EDI 856 and 810.
Native D365 integration for purchase order receipt, warehouse pick and ship confirmation, and automated invoice creation from confirmed shipments.
SBSA connects Cencora EDI directly to QuickBooks Online through a secure API, automatically converting purchase orders (POs) into sales orders and generating invoices.
SBSA connects Cencora EDI directly to QuickBooks Enterprise using the QuickBooks SDK or IIF import, automatically converting purchase orders (POs) into sales orders and generating invoices.
If your ERP or WMS isn't listed, SBSA builds a custom integration — flat-file imports, proprietary systems, and everything in between.
Manual EDI processing introduces errors, delays, and chargeback exposure. SBSA Technology automates the entire Cencora EDI cycle — from PO receipt through invoice and chargeback response — so your team focuses on fulfillment, not paperwork.
Automated PO Ingestion
855 Auto-Acknowledgment
ASN at Time of Shipment
Invoice Generation & Transmission
Chargeback Validation
Compliance Monitoring & Alerts
Common questions from manufacturers and suppliers beginning their Cencora EDI compliance journey — or looking to fix existing issues.
Cencora suppliers typically exchange the EDI 850 Purchase Order, 855 PO Acknowledgment, 856 Advance Ship Notice, 810 Invoice, and 997 Functional Acknowledgment as the core order-to-cash cycle. Suppliers participating in chargeback or rebate programs also exchange 844 and 849 chargeback documents, and many are asked to provide 852 Product Activity Data and 867 Product Transfer and Resale Reports for inventory visibility. SBSA handles the full set from a single integration.
Yes. SBSA's Cencora integration incorporates DSCSA-aligned transaction data and product tracing information alongside standard EDI documents, helping suppliers meet lot-level and serialized product traceability obligations required by pharmaceutical distributors.
Yes. SBSA provides pre-built connectors for SAP ECC/S4HANA, Oracle ERP Cloud, NetSuite, Microsoft Dynamics 365, and QuickBooks Online and Enterprise, mapping Cencora's EDI transactions directly to sales orders, shipment confirmations, and invoices in your ERP.
SBSA supports all three connection methods Cencora accepts: AS2 for direct encrypted transmission, SFTP for scheduled file-based exchange, and VAN routing through your existing value-added network provider. SBSA manages certificates, mailbox configuration, and ongoing monitoring for whichever method you use.
When Cencora submits an EDI 844 chargeback claim, SBSA validates the claimed WAC and contract price, quantity, and customer details against your contract data before you respond. Discrepancies are flagged so you can dispute or approve accurately via the EDI 849 response, reducing revenue leakage from incorrect chargebacks.
Yes. SBSA scales from small manufacturers running QuickBooks to large suppliers on SAP or Oracle. The underlying Cencora EDI mapping is the same; only the ERP connector and transaction volume differ, so onboarding effort stays proportionate to your business size.
Tell us your workflow — order-to-cash, chargebacks, or DSCSA traceability — and we'll build a complete integration plan including your ERP or QuickBooks connection.